網膜静脈分枝閉塞症の黄斑浮腫に対する柴苓湯の効果

Effect of peroral sairei-to on macular edema in branch retinal vein occlusion

（P−2-86）　むくみ（浮腫）の改善に有用とされる柴苓湯を，網膜静脈分枝閉塞症に伴う黄斑浮腫の症例に用い，その効果を検討した。対象は，1年以上経過観察できた柴苓湯（TJ114）を投与した投与群22例と投与しなかった非投与群29例である。柴苓湯の投与方法は，TJ114を毎食後3gずつ1日3回の服用とした。1年後の視力は，非投与群で55％が改善し21％に悪化がみられたのに対して，投与群では77％が改善し悪化はなかった。また，1年後の黄斑浮腫に関しては，非投与群で76％が改善，17％が不変，7％が悪化であったが，投与群では96％に改善が認められ，4％は不変であったが、悪化はなかった。従来の薬物療法および網膜光凝固療法では難治の症例に対して，柴苓湯の併用は有用と考えられた。

Sairei-to (TJ 114) has been claimed to relieve edema in Chinese medicine. It was given to 22 patients of branch retinal vein occlusion with macular edema at the daily dosis of 9 g/day 3.i.d. Another group of 29 patients with branch retinal vein occlusion with macular edema served as control. After one year, the visual acuity improved in 77% of cases in the treated group and deteriorated in none. In the control group, the visual acuity improved in 55% of cases and deteriorated in 21%. Macular edema improved in 96% and remained unchanged in 4% in the treated group. It improved in 76%, remained unchanged in 17% and deteriorated in 7% in the control group. The findings seemed to show the usefulness of sairei-to for branch retinal vein occlusion with macular edema, particularly in cases who fail to respond to other therapeutic modalities including photocoagulation.