網膜静脈分枝閉塞症における静脈血流速度と黄斑浮腫

Macular edema and velocity of retinal venous flow in branch retinal vein occlusion

要約　目的：網膜静脈分枝閉塞症での網膜動静脈血流動態と黄斑浮腫との関係の報告。対象と方法：3か月以内に網膜静脈分枝閉塞症が発症した2例2眼を対象とした。いずれも女性で，年齢は64歳と70歳である。レーザースペックルフローグラフィで，動静脈交差部前後の血流動態を複数回測定した。結果：網膜静脈では血流速度差と中心窩網膜厚に負の相関があり，動脈では血流歪度と中心窩網膜厚に正の相関があった。結論：網膜静脈分枝閉塞症では，動静脈交差の中枢と末梢側の不均衡により黄斑浮腫が増悪する。レーザースペックルフローグラフィによる血流動態の計測で，黄斑浮腫を予測できる可能性がある。

Abstract.　Purpose：To report the correlation between velocity of retinal venous flow and macular edema in branch retinal vein occlusion. Cases and Method：This study was made on 2 eyes of 2 females who presented with branch retinal vein occlusion of less than 3 months' duration. They were aged 64 and 70 years respectively. Laser speckle flowgraphy was repeatedly used to measure the hemodynamics proximal and distal to the arteriovenous crossing. Results：Foveal thickness was negatively correlated with the difference in velocity of venous blood flow between proximal and distal site of arteriovenous crossing. Foveal thickness was positively correlated with blood wave skew in the retinal artery. Conclusion：Macular edema may exacerbate by disproportion of hemodynamics between proximal and distal site of arteriovenous crossing. There is a possibility to predict macular edema in branch retinal vein occlusion by measuring the hemodynamics by laser speckle flowgraphy.