Peters奇形の親子例

Peters'anomaly in a baby and his father

　Peters奇形の親子例で，子にはAxenfeld-Rieger症候群を合併した症例を経験した。子は生後8日の男児で，両眼の中央部角膜に混濁があり，同部の角膜は菲薄，角膜と虹彩の間に虹彩の糸状突起がみられ，Peters奇形と診断した。また，Schwalbe環の隆起，隅角形成不全，虹彩実質低形成がみられ，Axenfeld-Rieger症候群を合併していた。しかし，3か月後，角膜混濁は軽減し，身体発育に伴い，隅角形成不全，虹彩実質低形成の程度はともに著明に軽減した。父は，32歳で，両眼の中央部角膜に混濁があり，同部では角膜虹彩間に虹彩の索状突起がみられた。

An 8-day-old male infant manifested, bilaterally, central corneal leucoma and thinning with adherent iris strands, leading to the diagnosis of Peters' anomaly. Both eyes also showed prominent ring of Schwalbe, goniodysgenesis and hypoplasia of iris stroma compatible with Axenfeld-Rieger syndrome. During the following 3 months, the corneal leucoma decreased, the iris hypoplasia became less pronounced and the goniodysgenesis became less prominent. The father of the patient, aged 32 years, showed bilateral corneal opacity which was less pronounced in the central cornea. Iris strands were adherent to the site of opaque cornea.