Psychological aspects of patients with blepharospasm treated by botulinum toxin Mika Suzuki 1 , Hiroko Yamazaki 1 , Atsushi Mizota 2 , Huang Hung-Jiun 2 , Kazuhide Tsukamoto 2 , Emiko Adachi-Usami 2 1Dept of Ophthalmol, Kohnodai Hosp, National Center of Neurology and Psychiatry 2Dept of Ophthalmol, School of Med Chiba Univ pp.769-772
Published Date 1998/5/15
DOI https://doi.org/10.11477/mf.1410905853
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We treated 25 patients with essential blepharospasm by topical injection of botulinum toxin A. Psychological aspects of the patients were evaluated by SDS and CMI testings. Dose-related responses were evaluated by eyelid muscle force and by Jankovic's rating score. The eyelid muscle force decreased significantly after injections of 1.25, 2.5 and 5 units per site. Jankovic's rating score improved in all patients after injections of 0.5, 1.25, 2.5 and 5 units per site with greater improvements with higher doses. There was no significant differences in the mean SDS score between patients and normal controls either before or after treatment. Six out of 23 patients showed depressive disorder with SDS ratings. Four cases showed neurotic disorder with CMI.

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