Outcome of treatment with botulinum toxin for mild blepharospasm Tomoyuki Ide 1 , Masaya Nishio 1 , Tone Suzuki 1 , Yasushi Uchino 1 , Makoto Chikuda 1 1Dept of Ophthalmol,Dokkyo Med Univ Koshigaya Hosp pp.1135-1138
Published Date 2010/7/15
DOI https://doi.org/10.11477/mf.1410103260
  • Abstract
  • Look Inside
  • Reference

Abstract. Purpose:To report the outcome of treatment with botulinum toxin for mild and severe blepharospasm. Cases and Method:This retrospective study was made on 28 cases of blepharospasm who received treatment with botulinum toxin in the past 5 years. The series comprised 8 males and 20 females. Seven cases were diagnosed with mild and 21 cases with severe blepharospasm. Outcome of treatment was evaluated by questionnaire using VFQ-25. Results:Subjective symptoms improved in all cases with mild blepharospasm. Five cases(71%)reported absence of complaints. Subjective symptoms improved in 61% and remained unchanged in 19% of cases with severe blepharospasm. There was no case who reported absence of complaints. VFQ-25 showed significant improvement in both groups. Comprehensive score after treatment averaged 84.3 in mild cases and 65.7 in severe cases. Conclusion:Treatment with botulinum toxin resulted in better outcome in patients with mild than severe blepharospasm.

Copyright © 2010, Igaku-Shoin Ltd. All rights reserved.


電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院