Japanese

Effect of botulinum toxin A on the force of eyelid closure Aki Hirai 1 , Yoshihiko Tsuyama 1 , Atsushi Mizota 1 , Emiko Adachi 1 , Hiroko Yamazaki 2 1Dept of Ophthalmol and Visual Sci, Graduate Sch of Med, Chiba Univ 2Dept of Ophthalmol, National Center of Neurol and Psychiat Kohnodai Hosp pp.543-546
Published Date 2002/4/15
DOI https://doi.org/10.11477/mf.1410907682
  • Abstract
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We treated 21 cases of essential blepharospasm and 19 cases of hemifacial spasm by injecting botulinum type A toxin into 5 sites of the eyelids. The therapeutic effect was evaluated by using the force of eyelid closure and Jankovic score as parameters. In cases of essential blepharospasm, the effect reached its maximum one month after in-jection to gradually decrease until one month later. In cases of hemifacial spasm, the effect reached its maximum one month after injection and lasted for 3 months. The findings show that injection of botulinum toxin A is effective for es-sential and hemifacial blepharospasm. While the force of eyelid closure and Jankovic score were useful in evaluating the therapeutic effect, the former was more valuable as an objective clinical means.


Copyright © 2002, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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