眼内悪性リンパ腫の1例

A case of malignant intraocular lymphoma

　71歳の女性で片眼性の後部ぶどう膜炎を初発症状とし，経強膜網脈絡膜生検でT細胞性眼内悪性リンパ腫と診断し得た1例を経験した。患者は診断確定後に頭蓋内病変，骨髄病変が出現したが，放射線治療と化学療法の併用で眼内病変・頭蓋内病変は消退した。原因不明のぶどう膜炎では，眼内悪性リンパ腫も念頭におき，早期に診断を確定し，治療することが重要である。

A 71-year-old female presented with posterior uveitis in the left eye of 3 weeks' duration. Intense vitreous opacity and exudate in the posterior fundus were main clinical features. Transscleral retinochor-oidal biopsy peformed 4 months later led to the diagnosis of T cell intraocular lymphoma. The patient later manifested involvements of central nervous system and bone marrow. Intraocular and central nervous system lesions subsided after radiation to the affected eye and the brain with additional intrathecal and intravenous chemotherapy. Intraocular lymphoma is a possibility in uveitis of unknown origin.