MPS2を用いた対照眼と中心性漿液性網脈絡膜症における黄斑色素光学密度の検討

Optical density of macular pigment in eyes with or without central serous chorioretinopathy measured by macular pigment screener（MPS2）

要約　目的：黄斑色素スクリーナー（MPS2）で測定した健常眼と中心性漿液性網脈絡膜症（CSC）の黄斑色素光学密度の報告。対象と方法：CSCのある16例16眼を対象とした。男性14例，女性2例で，平均年齢は55歳であった。CSCがない僚眼16眼と，健常な127例231眼の計247眼を対照とした。結果：対照眼での黄斑色素光学密度は，平均0.64±0.14で，年齢と屈折値には相関がなく，女性よりも男性が高かった（p＜0.05）。CSCの罹患眼での黄斑色素光学密度は，中心窩網膜厚と正の相関があり（R2＝0.53），中心窩網膜厚が薄いほど黄斑色素光学密度が低下した。結論：健常眼での黄斑色素光学密度は，年齢とは相関しなかった。CSC眼での黄斑色素光学密度は，対照眼または僚眼よりも有意に低く，慢性化したCSC眼でこの傾向が顕著であった。

Abstract.　Purpose：To report optical density of macular pigment in eyes with or without central serous chorioretinopathy（CSC）. Cases and Method：This study was made on 16 eyes of 16 cases with CSC. The series comprised 14 males and 2 females. The age averaged 55 years. Optical density of macular pigment was measured using a macular pigment screener（MPS2）. Findings were compared with those in 247 eyes that comprised 16 fellow eyes of CSC and 231 eyes of 127 healthy persons. Results：Optical density of macular pigment in healthy eyes averaged 0.64±0.14. The value was not correlated with age or refraction. It was significantly higher in males than females（p＜0.05）. Optical density of macular pigment in eyes with CSC was positively correlated with foveal retinal thickness（R2＝0.53）. It was lower in eyes with decrease in foveal retinal thickness. Conclusion：Optical density of macular pigment in healthy eyes showed no correlation with age. It was significantly lower in control or fellow eyes. This tendency was more manifest in chronic CSC.