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A case of macular coloboma with choroidal neovascularization treated by intravitreal aflibercept Hajime Takahashi 1 , Masayuki Ohnaka 1 , Katsuaki Miki 1 , Tadashi Nakauchi 1 , Kanji Takahashi 1 1Dept of Ophthalmol, Kansai Med Univ pp.1037-1042
Published Date 2015/7/15
DOI https://doi.org/10.11477/mf.1410211414
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Abstract. Purpose:To report a case of macular coloboma with choroidal neovascularization treated by intravitreal injection of aflibercept. Case:A 60-year-old male presented with impaired visual acuity in the right eye since 3 weeks before. He had been diagnosed with macular coloboma in the right eye and normal-tension glaucoma in the left 2 years before. Findings:Visual acuity was 0.1 right when corrected with −4.5 diopters and 1.2 left when corrected with −10 diopters. The right macula showed choroidal coloboma of 3 disc diameters across with subretinal hemorrhage and gray lesion. Fluorescein angiography showed hypofluorescence in the gray lesion followed by dye leakage. ICG angiography showed reticulated pattern in the area of gray lesion. Optical coherence tomography showed partial retinal defect and total choroidal absence. Retinal edema and choroidal neovascularization were present in the nasal retina. The right eye received 4 sessions of intravitreal injection of aflibercept. Subretinal hemorrhage disappeared with visual acuity of 0.3 8 months later. Conclusion:Intravitreal injection of aflibercept was effective in the present case of macular coloboma with choroidal neovascularization.


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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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