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要約 目的:点状内層脈絡膜症(punctate inner choroidopathy)に併発した脈絡膜新生血管(CNV)がベバシズマブの硝子体内投与で退縮した3症例の報告。症例と経過:3症例とも女性で,年齢は24,36,57歳であり,いずれも片眼性の発症であった。2眼には-8D,1眼には-2Dの近視があり,矯正視力はそれぞれ0.5,0.2,0.08であった。眼底後極部に白点が散在し,蛍光眼底造影でⅡ型CNVがあった。CNVを伴った点状内層脈絡膜症と診断した。1~3回のベバシズマブの硝子体内投与を行った。CNVは退縮し,視力はそれぞれ1.2,1.0,0.8に改善した。結論:3例の点状内層脈絡膜症に併発したCNVに対し,ベバシズマブの硝子体内投与が著効を示した。
Abstract. Purpose:To report 3 cases of punctate inner choroidopathy with choroidal neovascularization(CNV)treated by intravitreal bevacizumab. Cases and Findings:All the 3 cases were females and were aged 24,36 and 57 years respectively. All were unilaterally affected. Refraction was -8 diopters in 2 cases and -2 diopters in one. Corrected visual acuity was 0.5,0.2 and 0.08 respectively. All the affected eyes showed white dots scattered in the macular area. Fluorescein angiography showed type 2 CNV. CNV resolved after one to 3 sessions of intravitreal injection of bevacizumab. Visual acuity improved to 1.2,1.0 and 0.8 respectively. Conclusion:These cases illustrate that intravitreal bevacizumab may be effective for CNV in eyes with punctate inner choroidopathy.
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