雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

検索

書誌情報 詳細検索 by 医中誌

Japanese

Outcome of intravitreal aflibercept for polypoidal choroidal vasculopathy Yuko Nishikawa 1,2 , Kunihiko Akiyama 1,2 , Toshiaki Hirakata 1,2 , Kaoru Fujinami 1,2,3,4 , Ken Watanabe 1,2 , Toru Noda 1,2 1Dept of Ophthalmol, Nat Hosp Organ, Tokyo Med Cent 2Lab of Vis Physiol, Nat Inst of Sensory Organs, Tokyo Med Cent 3Dept of Ophthalmol, Keio Univ Sch of Med 4UCL Inst of Ophthalmol pp.1763-1768
Published Date 2014/12/15
DOI https://doi.org/10.11477/mf.1410200158
  • Abstract
  • Look Inside
  • Reference

Abstract. Purpose:To report the outcome of intravitreal injection of aflibercept for polypoidal choroidal vasculopathy(PCV). Cases and Method:This study was on 15 eyes of 15 cases of PCV. The series comprised 12 males and 3 females. Thirteen eyes had received other therapeutic modalities. The 15 eyes received intravitreal injection of 2.0mg aflibercept repeated 2 or 3 times at the interval of 4 weeks, followed by additional sessions when needed. The outcome was evaluated 6 months after start of treatment. Visual acuity was evaluated as logMAR. Results:Visual acuity averaged 0.34±0.37 before treatment and 0.36±0.49 6 months later. The difference was not significant. There was no difference in central retinal thickness before and 6 months of treatment. Thickness of retinal pigment epithelium detachment averaged 312±199μm before treatment and 152±136μm 6 months later. The difference was significant(p=0.002). Subretinal fluid was present in 7 eyes before treatment and in 2 eyes 6 months later. Conclusion:Intraviteal aflibercept for PCV showed decreased thickness of retinal pigment epithelium detachment after 6 months. There was no change in visual acuity or central retinal thickness. Subretinal fluid was absorbed completely in 5 out of 7 eyes after 6 months of treatment.


Copyright © 2014, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

関連文献

もっと見る

文献を共有