Japanese
English
- 有料閲覧
- Abstract 文献概要
- 1ページ目 Look Inside
- 参考文献 Reference
要約 目的:多発性後極部網膜色素上皮(MPPE)がある2例4眼に,低照射エネルギー光線力学的療法を行った報告。症例:症例はそれぞれ61歳と67歳の男性である。1例は1年前からステロイド薬の全身投与を受け,視力障害で当科を受診した。他の1例は多発性骨髄腫に対して10年前からプレドニゾロンを内服していた。3年前にMPPEが発症し,複数回の光凝固を受けたが改善しなかった。所見:両症例とも両眼のMPPEと診断し,1例には囊胞様黄斑浮腫があった。通常の半量のverteporfinを用いた低照射エネルギー光線力学的療法を両症例の両眼に行った。4眼中3眼で漿液性網膜剝離が改善し,中心窩下の脈絡膜厚が減少した。うち2眼で視力が改善し,4眼中1眼では所見に改善がなかった。結論:MPPEに対し,低照射エネルギー光線力学的療法が4眼中3眼で奏効し,1眼では無効であった。
Abstract. Purpose:To report the outcome of reduced-fluence photodynamic therapy for multiple posterior pigment epitheliopathy(MPPE)in 4 eyes of 2 cases. Cases:Both were males aged 61 and 67 years respectively. One case had been receiving peroral corticosteroid for one year. The other had had multiple osteoma and been treated by peroral prednisolone for 10 years. He had been diagnosed with MPPE 3 years before. Multiple sessions of photocoagulation were ineffective. Findings and Clinical Course:Both cases were diagnosed with bilateral MPPE. One case had cystoid macular edema. The affected 4 eyes received reduced-fluence photodynamic therapy using one-half dosis of verteporfin. Three eyes showed reduction of serous retinal detachment and subfoveal choroidal thickness. Visual acuity improved in 2 eyes. One eye failed to respond to treatment. Conclusion:Reduced-fluence photodynamic therapy was effective in 3 out of 4 eyes with multiple posterior pigment epitheliopathy. The treatment was ineffective in one eye.
Copyright © 2015, Igaku-Shoin Ltd. All rights reserved.