Central Cloudy Corneal Dystrophyの母子例

Familial occurrence of central cloudy corneal dystrophy

　central cloudy corneal dystrophyと思われる母子例を報告した．

　症例　は76歳女性，主訴は両眼の視力低下で角膜知覚低下を認め，両眼ともに角膜中央部に限局した実質全層にわたる円形の片雲状混濁を認めた．角膜厚は正常であった．さらに，本症例の第2子（44歳，女性），第3子（41歳，男性）の両眼角膜中央部に円形の淡い片雲状混濁を実質深層に認めた．視力及び角膜知覚の低下はなく，角膜厚も正常範囲内であった．なお，3症例中2症例で軽度の高コレステロール血症を呈していた．

A 76-year-old female presented with binocular visual deterioration as chief complaint. We obser-ved, by slitlamp biomicroscopy, disc-shaped cloudy areas in the central cornea in both eyes. The opac-ity involved the entire layers of the cornal stroma. The corneal thickness was normal. Corneal sensi-tivity was reduced.

Two members of her offspring, 44-year-old female and 41-year-old male, manifested disc -shaped nebulae located in the deep stromal layers in the central cornea bilaterally. Both cases manifested no decrease in vision or corneal sensitiv-ity. The corneal thickness was within normal range. Two of the three cases manifested mild hypercholesterolemia.

Rinsho Ganka (Jpn J Clin Ophthalmol) 42(7) : 867-870, 1988