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Investigation of interferon in Behçet's and Vogt-Koyanagi-Harada's diseases Fujiko Kato 1 , Shigeaki Ohno 1 , Hidehiko Matsuda 1 , Nobuhiro Fujii 2 , Tomonori Minagawa 2 1Department of Ophthalmology, Hokkaido University School of Medicine 2Department of Microbiology, Hokkaido University School of Medicine pp.1013-1016
Published Date 1980/7/15
DOI https://doi.org/10.11477/mf.1410208150
  • Abstract
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The serum levels of interferon (IF) were investi-gated in 46 patients with Behçet's disease, and 16 patients with Vogt-Koyanagi-Harada's (VKH) di-sease. IF assay was performed by the semi-micro, dye-binding method. It was shown that the signi-ficantly higher levels of IF was detected in both Behçet's and VKH diseases, than those of normal controls (Behçet's disease: p<0.0001, VKH disease: p<0.0001). The levels of IF were significantly decreased in acute stage of ocular attacks, and were increased again in the convalescent stage in Behçet's disease.


Copyright © 1980, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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