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Anticoagulant treatment of retinal vein thrombosis with a new synthetic anticoagulant Dextran Sulphate Masakichi Mikuni 1 , Takao Fueda 1 , Shigeo Kimura 1 1Dept. of Ophth., Niigata Univ. School of Medicine. pp.1515-1524
Published Date 1960/10/15
DOI https://doi.org/10.11477/mf.1410207054
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Synthetic anticoagulant, Dextran Sulphate was administered for 7 to 10 days ; on the first day by four times intravenous injections, on the second day thrice, and thereafter once or twice daily intermittently. The dose of injection was kept each time at 300mg. The frequency and interval of injections were controlled by determinaing clotting time as an indicator.

A cumulative effect in clotting time was observed after the repeated injections. There was a marked fall in serum total cholesterol and platelet count during the treatment.


Copyright © 1960, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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