Rinsho Ganka Volume 65, Issue 4 (April 2011)

Effect of astaxanthin consumption on hydroperoxides in the aqueous Hirotaka Hashimoto 1,2 , Kiyomi Arai 2 , Yukihiro Okamoto 2 , Jiro Takahashi 3 , Makoto Chikuda 2 , Yoshitaka Obara 4 1Tsukuba Hashimoto Optical Clin 2Dept of Ophthalmol,Dokkyo Med Univ Koshigaya Hosp 3Fuji Chemical Ind Co 4Dokkyo Med Univ pp.465-470
Published Date 2011/4/15
DOI https://doi.org/10.11477/mf.1410103607
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Abstract. Purpose:To report changes in hydroperoxides in the aqueous following peroral astaxanthin in humans. Cases and Method:This prospective study was made on 35 patients with senile cataract who were duly informed and gave written consent. During surgery in one eye,the primary aqueous was collected and was quantitated for total amount of hydroperoxides. After surgery,patients were given astaxanthin at the daily dosis of 6 mg for 2 weeks. The same procedure was repeated during surgery on the fellow eye 2 weeks later. Results:Total hydroxides in the aqueous significantly decreased 2 weeks later(p<0.05). The decrease was significant in males and not significant in females. The decrease was significant in males with diabetes and in females without. The decrease was significant in females with diabetes and males without. Conclusion:Peroral consumption of astaxanthin may result in decrease of hydroperoxides in the aqueous.

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65巻4号 (2011年4月)
電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院