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Intravitreal injection of bevacizumab in the treatment of central serous chorioretinopathy Toshiya Sakurai 1 , Masashi Sakamoto 1 , Sinichi Sugita 1 , Gen Takaoka 1 , Taku Miyaura 1 , Tomoyuki Yamada 1 , Sachiko Fukuoka 1 , Ryotaro Tano 1 , Hisashi Takenaka 1 , Kokuchu Cho 1 , Tomiya Mano 1 1Tane Mem Eye Hosp pp.1365-1370
Published Date 2010/8/15
DOI https://doi.org/10.11477/mf.1410103306
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Abstract. Purpose:To report the outcome of intravitreal injection of bevacizumab for central serous chorioretinopathy(CSC). Cases and Method:This study was made on 7 eyes of 7 patients who had recurrence of CSC persisting for 3 months or longer. The series comprised 5 males and 2 females. The age ranged from 30 to 61 years,average 44 years. They were treated by intravitreal injection of 1.25 mg bevacizumab and were followed up for an average of 14.5 months. Results:CSC disappeared in 4 cases within 3 months of treatment. The finding was confirmed by optical coherence tomography. The other 3 cases received repeat injection. CSC disappeared in 2 cases within 4 months after the initial treatment and in one case within 12 months. CSC disappeared after an average of 3.8 months in the whole series. Visual acuity improved or was maintained in all the 7 cases after 12 months of treatment. Hyperfluorescence and dye leakage decreased after treatment when seen by fluorescein or ICG angiography. Conclusion:Intravitreal injection of bevacizumab was effective for recurrence of CSC.


Copyright © 2010, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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