Japanese

Treatment of age-related macular degeneration by intravitreal bevacizumab followed by photodynamic therapy Toshiya Sakurai 1 , Takatoshi Maeno 1 , Taiga Kinoshita 1 , Tomoyuki Yamada 1 , Ryotarou Tano 1 , Sachiko Fukuoka 1 , Minoru Yoshida 1 , Hirohisa Kawamura 1 , Hisashi Takenaka 1 , Cho Kokuchu 1 , Tomiya Mano 1 1Tane Memorial Eye Hosp pp.951-955
Published Date 2008/6/15
DOI https://doi.org/10.11477/mf.1410102284
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Abstract. Purpose:To report the outcome of age-related macular degeneration treated by intravitreal bevacizumab followed by photodynamic therapy. Cases and Method:This retrospective study was made on 6 eyes of 6 patients of age-related macular degeneration associated with serous or hemorrhagic detachment of retinal pigment epithelium. The series comprised 4 males and 2 females. The age ranged from 60 to 88 years, average 73 years. Each case received intravitreal injection of 1.25mg bevacizumab followed by photodynamic therapy the next day. Visual acuity was evaluated in terms of logMAR. Results:Six month after treatment, visual acuity improved by 2 lines or more in 4 eyes(67%)and remained unchanged in 2 eyes(33%). Detachment of retinal pigment epithelium regressed in 5 eyes. Conclusion:Intravitreal bevacizumab followed by photodynamic therapy may be effective for age-related macular degeneration associated with detachment of retinal pigment epithelium.


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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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