杆体機能障害の改善を認めた両眼性AZOORの1例

A bilateral case of acute zonal occult outer retinopathy（AZOOR）with improved rod dysfunction

要約　目的：杆体機能障害が改善した両眼性AZOOR（acute zonal occult outer retinopathy）の症例の報告。症例：34歳女性が10日前からの右眼の光視症と下方視野欠損で受診した。所見：矯正視力は左右とも1.5で，前眼部から眼底まで異常所見はなかった。視野検査で右眼に傍中心暗点と下方視野の暗点，左眼に盲点の拡大があった。全視野網膜電図で錐体と杆体の障害が両眼にあり，多局所網膜電図で視野異常の部位と一致する応答密度の低下があった。視野と網膜電図とから両眼性のAZOORと診断した。発症から7か月後に杆体機能が改善し，錐体機能障害は持続した。結論：本症例では，AZOORによる機能回復の過程に錐体と杆体とで違いがあった。

Abstract.　Purpose：To report a bilateral case of acute zonal occult outer retinopathy（AZOOR）with improvement in the impaired rod function. Case：A 34-year-old female presented with photopsia and impaired visual field defect in her right eye since 10 days before. Findings：Corrected visual acuity was 1.5 in either eye. Both eyes were free of abnormal findings in the anterior segment,optic media or the fundus. Goldmann perimetry showed paracentral scotoma and defect in the inferior sector in the right eye. The blind spot was enlarged in the left eye. Ganzfeld electroretinography（ERG）showed impaired cone and rod function. Multifocal electroretinography showed reduced responses in areas of impaired visual field. These findings led to the diagnosis of AZOOR. Rod function improved and cone function remained impaired 7 months after onset. Conclusion：This case illustrates that cone and rod function may differ in the course of recovery after episode of AZOOR.