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要約 目的:網膜静脈分枝閉塞症に続発した黄斑浮腫に対しベバシズマブの硝子体注入を行った症例の8か月間の経過報告。症例と経過:40歳男性が2日前からの左眼変視症と視野異常で受診した。矯正視力は右1.5,左1.2であり,左眼に黄斑浮腫を伴う網膜静脈分枝閉塞症の所見があった。5か月後に黄斑浮腫のため視力が0.5に低下し,ベバシズマブの硝子体注入を行った。光干渉断層計による中心窩厚が減少し,4週間後に視力が1.0に改善した。その5週間後に変視症が増悪し,中心窩厚が増加し,ベバシズマブの第2回注入を行った。自覚症状と黄斑所見は急速に改善した。初回治療から8か月後の現在,視力は1.2に維持されている。結論:網膜静脈分枝閉塞症に続発した黄斑浮腫に対してベバシズマブの硝子体注入を2回行い,視力低下,黄斑浮腫,多局所網膜電図の応答密度が改善した。
Abstract. Purpose:To report the 8-month outcome of intravitreal injection of bevacizumab for branch retinal vein occlusion with macular edema. Case and Findings:A 40-year-old male presented with metamorphopsia and visual field defect in his left eye since two days before. Corrected visual acuity was 1.5 right and 1.2 left. His left eye showed branch retinal vein occlusion with macular edema. The left eye received intravitreal injection of bevacizumab after decrease of visual acuity to 0.5 five months later. The foveal thickness decreased and visual acuity increased to 1.0 four weeks later. A second injection was performed after exacerbation of metamorphopsia 5 weeks later. Subjective and objective findings improved including those by optical coherence tomography and multifocal electroretinogram. Visual acuity is 1.2 now 8 months after the initial treatment. Conclusion:Intravitreal bevacizumab was effective for branch retinal vein occlusion with macular edema.
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