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Two herediary cases of retinoblastoma that rapidly multiplied after detection one month after birth Teppei Kajita 1 , Yuka So 1 , Yoshikazu Hatsukawa 1 , Masahiro Yasui 2 , Keisei Kawa 1 1Dept of Ophthalmol, Osaka Med Cent and Research Inst for Mater and Child Health 2Dept of Hematol and Oncol, Osaka Med Cent and Research Inst for Mater and Child Health pp.1215-1220
Published Date 2007/7/15
DOI https://doi.org/10.11477/mf.1410101839
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Abstract. Purpose:To report two cases of hereditary retinoblastoma that rapidly multiplied after detection soon after birth. Cases:Retinoblastoma was detected in a female infant 5 days after birth and a male infant one month after birth. Only one eye was affected in both cases. The tumor was present as a single focus in the former and as 5 foci in the latter. Their fathers had been patients of retinoblastoma. The tumors became scarred after photocoagulation. Soon later, retinoblastoma developed bilaterally and grew rapidly in both cases in spite of photocoagulation and cryotherapy. Systemic chemotherapy was effective in preventing further occurrence of retinoblastoma in both cases after one year of age. Conclusion:Early-onset hereditary retinoblastoma need utmost care regarding occurrence and recurrence of tumors.


Copyright © 2007, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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