Prolonged QTc Intervals in Parkinson's Disease:Relation to Sudden Death and Autonomic Dysfunction Fumiko Ishizaki 1 , Toshihide Harada 1 , Haruyuki Yoshinaga 2 , Takayasu Nakayama 1 , Yasuhiro Yamamura 1 , Shigenobu Nakamura 1 1Third Department of Internal Medicine, Hiroshima University School of Medicine 2Kojika-Gakuen Institute and Hospital of Social Welfare Foundation Keyword: ECG , QT interval , sudden death , Parkinson's disease , autonomic dysfunction pp.443-448
Published Date 1996/5/1
DOI https://doi.org/10.11477/mf.1406900946
  • Abstract
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Sudden death has been reported in Parkinson's disease (PD), but the cause of death has not been fully clarified. A prolonged QT interval on the electrocardiogram (ECG) of patients without car-diac dysfunction is an independent risk factor for sudden death regardless of etiology. QT prolonga-tion is believed to be related to cardiac autonomic dysfunction. We suspected that QTc intervals, as well as QT intervals, might be related to the clinical characteristics of PD and to the function of the autonomic nervous system in PD and also postulat-ed a relationship between QTc prolongation and sudden death in PD.

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