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Corticobasal degeneration(CBD)と進行性核上性麻痺(PSP)において,正中神経刺激により得られた体性感覚誘発電位(SEP)を比較検討した.CBD群とPSP群を比較したところ,潜時,振幅ともに有意差はなかった。SEPの左右差に注目すると,CBD群では頭頂部SEPにおいて振幅低下の左右差が有意に認められた。両疾患の鑑別にSEPが有用である可能性が示唆された。
It is by no means easy to make an early differential diagnosis between corticobasal degene-ration (CBD) and progressive supranuclear palsy (PSP), because both disorders occasionally show similar clinical features such as parkinsonism, su-pranuclear gaze palsy, or dementia. In the present study, we studied somatosensory-evoked potentials (SEPs) in 4 CBD and 8 PSP patients. SEPs after median nerve stimulation (0.2 ms square wavedelivered with a frequency of 1 Hz) were recorded from bilateral parietal and midfrontal electrodes.
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