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A CASE OF GARCIN'S SYNDROME WITH A NASOPHARYNGEAL CANCER Ken'ichi Kamata 1 , Hideyuki Harano 1 , Mitsuhiro Hanawa 1 , Osamu Seino 1 , Hiroyuki Nemoto 1 , Kosaku Nakayama 1 , Mutsuro Shiina 2 1Dept. of Neurosurgery, Seirei Hamamatsu Hospital 2Dept. of Otolaryngology, Seirei Hamamatsu Hospital. pp.1045-1050
Published Date 1972/8/1
DOI https://doi.org/10.11477/mf.1406203173
  • Abstract
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A case of Garcin's syndrome-Le syndrome paraly-teique unilaterals globale des nerfs craniens-was experienced.

A patient was 58-year-old male with a nasophary-geal cancer, who showed the paresis of the I, III, IV, VI, VII, VIII, IX, X, XI and XII cranial nerves on the left side, and I, VIII, IX, X and XII on the right side.

No disturbance of sensory and motor system were observed on extremities and no signs of increased intracranial pressure.

The Plain X-rays of his skull disclosed destructionof the base. Nasopharyngeal epidermoid cancer was proved by autopsy.

At the present time, "Garcin's syndrome" is characterized by : 1) unilateral involvement of all cranial nerves, 2) absence of any signs of involve-ment of motor or sensory systems on extremities, 3) absence of any signs of increased intracranial pressure, 4) abnormal X-ray findings of the base of the skull.

In far advanced stages the lesions may also spread to the opposite side. The clinical picture is nearly maintained by neoplastic process of the base.

As point out by Pisi, it is suggested that the term "Garcin's syndrome" be replaced by 'syndrome of unilateral, multiple, extensive and progressive involvement of the cranial nerves'.

We support Pisi's comment considering our case with many references for Garcin's syndrome.

In addition, we discussed about the difference of Garcin's syndrome and multiple cranial neuropathy.


Copyright © 1972, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

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