Haemodynamic Effects of Intravenous Isosorbide Dinitrate in Congestive Heart Failure Nobuhisa Ohgitani 1 , Takehito Taniura 1 , Noriyuki Akehi 1 , Hiroshi Kimura 2 , Makoto Yamada 3 , Katuji Imai 3 1Kitaosaka Hospital, Cardiovascular Division 2Kitaosaka Hospital, Cardiovascular Surgery 3Takatuki Hospital Keyword: 急性心不全 , isosorbide dinitrate , 血行動態 , congestive heart failure , isosorbide dinitrate , hemodynamics pp.1085-1091
Published Date 1992/11/15
DOI https://doi.org/10.11477/mf.1404900570
  • Abstract
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The effects of intravenous infusion of isosorbidedinitrate (ISDN) were evaluated in 22 patients with congestive heart failure. These patients did not receive vasodilater therapy before this study. Seven of these patients (two bolus groups of 5.0 mg and 7.5 mg each) were infused bolusly. The mean PA, PCWP and mean RA decreased for 5 min and, after 60 min, they were back to the original levels. The mean Ao had an accentuated change when the 7.5mg bolus was injected, but, apart from that, changes were minimal. The CI changed little and upwardly.

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