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Echocardiographic assessment of pulmonary hypertension in the patients with Down syndrome who have no congenital heart disease Yasutaka Kamiya 1 , Nobuyuki Kiyozawa 1 , Naoki Nomoto 2 1Department of Pediatrics, Kyoto Prefectural University of Medicine 2Kyoto City Child Welfare Center, Department of Pediatrics pp.1087-1091
Published Date 1987/10/15
DOI https://doi.org/10.11477/mf.1404205136
  • Abstract
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We studied echocardiographic assessment of pul-monary hypertension in the patients with Down syndrome who have no congenital heart disease. Right ventricular pre-ejection period/right ventricu-lar ejection time (RPEP/RVET) were measured from pulmonary valve echo in 23 patients and 20 normal children. Absence of the "a" dip of pulmonary valve and presence of right ventricular dilatation were evaluated too. The mean -SD of RPEP/RVET was 0.24±0. 04 (range 0.16~0.35) in the patients and 0.21±0. 03 (range 0.15~4.26) in normal children. The mean RPEP/RVET was significantly greater in the patients than in normal children (p<0.05). In the patients, RPEP/RVET greater than 0.35 was found in one case, absence of the "a" dip in 3 cases, and right ventricular dilatation in one case. These data suggested that presence of pulmonary hyperten-sion should be considered in the patients with Down syndrome who have no congenital heart disease.


Copyright © 1987, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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