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Clinical findings and prognosis of aortitis syndrome associated with pulmonary vascular disease Tatsuo Fujioka 1 , Ken Tanaka 1 , Izumi Yamaguchi 1 , Sanae Takahashi 1 , Takeo Kubokura 1 , Shin-ichi Kimata 1 , Morie Sekiguchi 1 , Mizuka Kondo 1 , Minoru Shibuya 1 , Koshichiro Hirosawa 1 1Dept. of Int. Med., The Heart Institute of Japan, Tokyo Women's Medical College pp.723-728
Published Date 1984/7/15
DOI https://doi.org/10.11477/mf.1404204481
  • Abstract
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Although pulmonary vascular changes in aortitis syndrome were described by Ohta in 1940, little attentions have been given to these lesions or to the natural history of cases with them.

The clinical, hemodynamic and pulmonary angiographic features have been studied in patients with pulmonary vascular involvements.

Such involvements were found in 30 (38%) of 80 cases with aortitis syndrome. In most of the 30 cases, the aortic lesions were not always limited to the aortic arch, but were also found in the thoracic and abdominal portions of the descending aorta.

Moreover, other complications, such as aortic regurgitation (63%), coronary artery involvement (20%), hypertension (63%) and renal artery in-volvement (40%) were found more often in the patients with pulmonary involvement than in those without these changes. We found that changes in the main pulmonary artery and its branches are correlated with systolic pulmonary pressure. Pulmonary hypertension was found in 77% of the 30 cases. The patients with pulmonary hyperten-sion had pulmonary symptoms, such as hemo-ptysis, pulmonary infarction and right-sided heart failure, and their prognosis was worse than that of the other patients.

The present study shows that patients with pulmonary involvements should be followed up carefully.


Copyright © 1984, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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