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Japanese

Combined vasodilator and positive inotropic agent therapy in severe congestive cardiomyopathy Kenji Nakai 1 , Yoshiaki Osamura 1 , Sanae Takahashi 1 , Michiaki Hiroe 1 , Shin-ichi Kimata 1 , Morie Sekiguchi 1 , Koshichiro Hirosawa 1 1Dept. of Int. Med., The Heart Institute Japan, Tokyo Women's Medical College pp.1003-1008
Published Date 1978/10/15
DOI https://doi.org/10.11477/mf.1404203264
  • Abstract
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The hemodynamic effects of combined administration of vasodilator with positive inotropic agent were evaluated in two patients in low output state who had severe congestive cardiomyopathy. In these cases, cardiac output was markedly decreased (1.71 and 1.12L/min) and pulmonary diastolic pressure was remarkably elevated (26 and 52 mmHg). No significant effects were revealed by separately administration of vasodilator or positive inotropic agent. However, combination of these drugs increased cardiac output and reduced PA diastolic pressure.


Copyright © 1978, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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