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Effect of ACTH on the actions of bronchoactive agents and on cyclic nucleotide content in guinea pig tracheal tissues Satoshi Kitamura 1 , Yoko Ishihara 1 , Yukihiko Sugiyama 1 , Shuichi Yoneda 1 1The Third Department of Internal Medicine, University of Tokyo pp.515-521
Published Date 1979/5/15
DOI https://doi.org/10.11477/mf.1404203367
  • Abstract
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The effect of ACTH on the actions of various bronchoactive agents and on cyclic nucleotide contents in guinea pig lung and tracheal tissues was examined.

Male guinea pigs, weighing 250-300g, were used. Guinea pig tracheal strips were removed, suspended in bioassay glass jackets and superfused with Krebs-Henseleit solution at 37℃ saturated with oxygen and carbon dioxide (95 : 5, v/v). Contraction and relaxation of guinea pig tracheal strips were detected by an isotonic transducer and displayed on a polyrecorder. The cyclic nu-cleotide content of guinea pig lung and tracheal tissues were determined by radioimmunoassay method.


Copyright © 1979, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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