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The High Prevalence of Periodontitis in Patients with Marfan Syndrome Mieko Aoki 1 , Yasushi Imai 1 , Daishi Fujita 1 , Naomi Ogawa 1 , Masayoshi Kato 1 , Hiroshi Nishimura 1 , Jun-ichi Suzuki 1 , Yasunobu Hirata 1 , Ryozo Nagai 1 1Department of Cardiovascular Medicine, University of Tokyo Hospital Keyword: マルファン症候群 , 歯周病 , 地域歯周疾患指数(CPI) , Marfan syndrome , periodontitis , CPI pp.939-942
Published Date 2011/9/15
DOI https://doi.org/10.11477/mf.1404101788
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 Marfan syndrome is a connective tissue disorder with autosomal dominant inheritance.

 The disease affects mainly the skeletal,cardiovascular,and ocular systems. Patients with this syndrome often demonstrate oral and maxillofacial manifestations including highly arched palate with crowding of teeth. In order to evaluate the clinical characteristics in Japanese Marfan syndrome patients,we evaluated the periodontal status of those patients who were diagnosed as Marfan syndrome according to the Ghent nosology(n=20). The results showed that the number of teeth present was 27. Probing pocket depth were 2.815±0.624mm,bleeding on probing 11.567±8.394%,and percentages of CPI(community periodontal index)codes 3 or 4 75%. Our results demonstrate the significantly high prevalence of severe periodontitis in patients with Marfan syndrome. The connective tissue disorder in Marfan syndrome may also increase susceptibitity to inflammatory breakdown of periodontal tissue.


Copyright © 2011, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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