超拡大内視鏡による潰瘍性大腸炎関連腫瘍診断の現状と課題

The Current Status and Issues of Ultra-high Magnifying Endoscopy for UC Associated Cancer Diagnosis

要旨●潰瘍性大腸炎の長期経過例にdysplasiaやcolitic cancerが高率に合併することはよく知られている．背景粘膜に炎症を伴うため，早期の内視鏡診断は容易ではない．近年，超拡大内視鏡（EC）による生体内での細胞レベルの観察が可能となり，UC関連腫瘍のEC観察を経験している．今後，症例を重ねることで，EC診断の精度が上がり，UC関連腫瘍の診断に寄与すると考える．

　It is well known that prolonged UC（ulcerative colitis）is associated with an increased risk of colorectal cancer. However, detection of dysplasia in UC patients is challenging because of mucosal inflammation. Recently, EC（endocytoscopy）has enabled us to observe lesions at the cellular level in vivo. This tool allowed us to observe colitic cancer, which will contribute toward the early detection and diagnosis of tumors associated with UC.