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Indication and Pitfalls of Endoscopic Resection for Ulcerative Colitis-associated Neoplasia Akira Matsui 1 , Junnosuke Hayasaka 1 , Satoshi Yamashita 1 , Daisuke Kikuchi 1 , Takayuki Okamura 1 , Yorinari Ochiai 1 , Yugo Suzuki 1 , Yumiko Fukuma 1 , Yutaka Mitsunaga 1 , Nobuhiro Dan 1 , Masami Tanaka 1 , Kosuke Nomura 1 , Hiroyuki Odagiri 1 , Shu Hoteiya 1 1Department of gastroenterology, Toranomon Hospital, Tokyo Keyword: dysplasia , 水平断端 , 内視鏡的粘膜下層剝離術 , ESD , sporadic tumor pp.159-166
Published Date 2020/2/25
DOI https://doi.org/10.11477/mf.1403201943
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 The standard therapy for ulcerative colitis-associated neoplasia, particularly high-grade dysplasia and colorectal cancer, is total colectomy. Because of recent increasing effectiveness of anti-inflammatory drug treatment and surveillance endoscopy, dysplasia and intramucosal cancer can be diagnosed endoscopically. We investigated the characteristics of ulcerative colitis-associated neoplasia that had undergone endoscopic submucosal dissection for the purpose of curative resection. We considered that pitfalls in endoscopic resection for ulcerative colitis-associated neoplasia included difficulty in identifying the demarcation line because of the low horizontal margin-negative rate and the high rate of synchronous tumors. Therefore, the indication for endoscopic resection in high-grade dysplasia and intramucosal cancer is a tumor in which a demarcation line is identified with surrounding biopsy area. Following resection, it was thought that endoscopy every 4-6 months was necessary.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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