Diagnosis of Early Stage Gastrointestinal Cancer Invasion Depth via Pit Pattern Observation Hiroshi Kawano 1 , Osamu Tsuruta 2,3 , Erina Ueno 1 , Masayuki Sawada 1 , Tetsuhiro Noda 2 , Shuichiro Nagata 2 , Yasuhiko Maeyama 2 , Keiichi Mitsuyama 2 , Takuji Torimura 2 1Division of Gastroenterology, St Mary's Hospital, Kurume, Japan 2Division of Gastroenterology, Department of Medicine, Kurume University, Kurume, Japan 3Division of Endoscopy, Kurume University Hospital, Kurume, Japan Keyword: 早期大腸癌 , pit pattern観察 , 深達度診断 , 拡大内視鏡 , NBI pp.676-685
Published Date 2015/5/24
DOI https://doi.org/10.11477/mf.1403200295
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 When we diagnosed colorectal neoplasms with magnification of pit patterns under crystal violet staining, the adenoma and Tis-T1a cancer differential diagnostic accuracy was 80%, the cancer diagnosis sensitivity was 43.8%, the specificity was 93.9%, the cancer invasion depth diagnostic accuracy was 84.8%, the T1b cancer invasion depth sensitivity was 77.4%, and the specificity was 89.6%. Although there are cases in which diagnosis cannot be performed because of the necessity of cleaning and staining the lesions, the slight complexity of the procedure, the presence of mucus, hemorrhaging from the lesion, and inadequate staining, diagnosis by magnification of pit patterns under crystal violet staining is a highly accurate diagnostic method. When cancer is suspected in conventional endoscopic observation and narrow-band imaging magnification and some kind of treatment is required, it is best to closely examine the lesion's properties with pit pattern magnification and diagnose its invasion depth. However, it is important to keep in mind that this information about the lesion surface gleaned from pit pattern magnification is a very small portion of the overall information.

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