Stomach and Intestine(Tokyo) Volume 50, Issue 4 (April 2015)

Realities of the Detection of Multiple Metachronous Lesions after Colonoscopic Treatment for Early Colon Cancer Hiroaki Sumie 1 , Osamu Tsuruta 1,2 , Michita Mukasa 1 , Hikaru Yoshida 1 , Atsushi Hinosaka 1 , Shuichirou Nagata 1 , Tetsuhiro Noda 1 , Yasuhiko Maeyama 1 , Shuji Sumie 1 , Hiroshi Kawano 3 , Keiichi Mitsuyama 1 , Takuji Torimura 1 1Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan 2Division of Endoscopy, Kurume University Hospital, Kurume, Japan 3Division of Gastroenterology, St Mary's Hospital, Kurume, Japan Keyword: 早期大腸癌 , 内視鏡治療 , 異時性多発病変 , Japan polyp study , national polyp study pp.385-392
Published Date 2015/4/25
  • Abstract
  • Look Inside
  • Reference

 In this study, we investigated the state of the detection of multiple metachronous lesions in 87 patients with early-stage colorectal cancer who had undergone colonoscopic treatment at our institution and were followed-up for at least one year. The cumulative detection rate of metachronous multiple lesions five years after colonoscopic treatment was 56.7%. Examination of clinicopathological characteristics of multiple metachronous lesions indicated that they tended to develop as a single lesion and occur in the right large intestine, and most were smaller than 10mm. The clinical course of multiple metachronous lesions was favorable both in patients who were treated and those who only underwent follow-up observations. The results of multivariate analysis of risk factors of multiple metachronous lesions revealed that an independent risk factor was the presence of three or more synchronous polyps. There is no established appropriate surveillance method for early-stage colorectal cancer after colonoscopic treatment; therefore, more research regarding this topic is needed in the future.

Copyright © 2015, Igaku-Shoin Ltd. All rights reserved.


50巻4号 (2015年4月)
電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院