Japanese

Villous Tumor of the Stomach, Report of a Case Takumi Nambu 1 , Mitsuo Iida , Takayoshi Nagata 2 , Akinori Iwashita 3 , Takeshi Kohi 4 1THe Second Department of Internal Medicine, Faculty of Medicine, Kyushu University 2The First Department of Surgery, Faculty of Medicine, Kyushu Universty 3The Second Department of Pathology, Faculty of Medicine, Kyushu University 4Kohi Ichoka Iin pp.187-193
Published Date 1986/2/25
DOI https://doi.org/10.11477/mf.1403110103
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 A 59-year-old man was admitted to the hospital with a 3-month history of epigastralgia. On physical examination the patient appeared thin but well. Laboratory findings revealed hypoproteinemia (total rotein 5.2g/dl, albumin 3.2g/dl)and hypocalcemia(serum calcium 7.7mg/dl). Upper gastrointestinal series demonstrated two pliable, lobulated tumors inthe distal stomach, both of which showed the lacy “soap-ubble” appearance characteristic of the villous tumor. One of them prolapsed into the duodenal bulb. Endoscopic view of the tumors showed a lobulated surface with mild reddening. The tumor was so friable that it was easy to insert the biopsy forceps into the tumor deeply. The partial gastrectomy was performed, because of the possibility of focal cancer, although histological examination of the biopsy specimen revealed adenoma(groupIII). There were two sessile protubelant lesions, measuring 12×9.5×1.5cm and 2×1.5×3.5cm respectively, in the resected stomach. Both of them had a shaggy surface composed of numerous frond-like processes. Microscopically the two tumors consisted of finger-like projections of neoplastic epithelium with a lamina propria projecting towards the lumen, i. e. villous adenoma. The larger one had small foci of well differentiated adenocarcinoma. Two days after the operation, hypopro. teinemia and hypocalcemia improved(total protein 6.7g/dl, albumin 3.8g/dl, calcium 8.6mg/dl). It is suggested that hypoproteinemia was due to proteinlosing from the villous tumor.


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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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