雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

Stomach and Intestine(Tokyo) Volume 16, Issue 12 （December 1981）

胃と腸 16巻12号（1981年12月発行）

Japanese English

症例

胃燕麦細胞癌を含む三重複癌の1剖検例 Multiple Cancers of the Stomach Including Oat-cell Carcinoma, an Autopsy Case 藤沢和明 ^1,4 , 岩下明徳 ³ , 上野裕巳 ¹ , 松坂俊光 ² , 山田寛保 ² , 滝原哲一 ² K. Fujisawa ^1,4 , A. Iwashita ³ , H. Ueno ¹ , T. Matsusaka ² , H. Yamada ² , T. Takihara ² ¹国立福岡中央病院内科 ²国立福岡中央病院外科 ³九州大学医学部第2病理 ⁴現九州大学医学部第3内科 ¹Department of Internal Medicine, Fukuoka National Central Hospiral ²Department of Surgery, Fukuoka National Central Hospiral ³The Second Department of Pathology, Faculty of Medicine, Kyushu University pp.1349-1354

発行日 1981年12月25日 Published Date 1981/12/25

DOI https://doi.org/10.11477/mf.1403108313

PDF(4965KB)

有料閲覧

Abstract 文献概要
1ページ目 Look Inside

　胃の燕麦細胞癌は非常にまれで，世界でもほとんど報告されていない．われわれは胃燕麦細胞癌に早期胃癌および進行胃癌の3者が，同時にかつ独立して存在した世界で最初の1例を経験したので報告する．

　A 61-year-old woman, complaining of epigastric pain, with hereditary disposition of gastric cancer was seen in our hospital. x-ray and endoscopic examinations revealed four lesions in the stomach. The lesion No.1 was a giant tumor in the anterior wall of the antrum: lesion No.2 a slight protruding lesion in the greater curvature of th antrum. Lesions No.3 and No.4 were small elevated lesion in the angle.

Pathohistology obtained by biopsy from the lesion No.1 showed undifferentiated lymphosarcoma, the lesion No.3 papillary adenocarcinoma. Gastrectomy was performed. The resected specimen showed that the lesion No.1 was Borrmann 1type, 6×6cm oatcell carcinoma, with brown irregular surface: the lesion No.2, type I early gastric cancer, 1.8×1.4cm, well differentiated adenocarcinoma: the lesion No.3, Borrmann 2 type, 2.4×2.0cm, well differentiated adenocarcinoma. The lesion No.4 was hyperplastic polyp. The patient died of cachexia six months after operation.

　Oat-cell carcinoma of the stomach is very rare and in 1976, only four cases were reviewed in the literature. There have been no other report ssince that time.

　On routine histologic examination, the tumor cells were arranged homogeneously in sheets and incomplete alveolar pattern separated by a delicate fibrous stroma, showing streams of cells and rosettes or ductule-like structures in smaller parts. Most tumor cells were almost uniformly small, round or oval but occasionally spindle-shaped, and had intensely hyperchromatic nuclei and scanty cytoplasm. The nucleoli were not prominent, and mitotic figures were frequent. Moderate permeation of the venules within the gastric wall by the tumor cells was recognized. These histologic features were compatible with those of oat-cell carcinoma of the lung. The silver impregnation by Grimelius' method was significantly positive for most of the neoplasti ccells. Fontana Masson method was negative. PAS and alcian blue stainings were both negative.