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化学療法により消褪したBorrmann1型胃癌症例を経験したので,主にX線,内視鏡,生検所見を提示し,治療内容を説明し,この症例についての考えを述べてみたい.
患 者:70歳 主婦
主 訴:腹痛,立ちくらみ,全身倦怠感
家族歴:兄が食道癌で死亡
既往歴:20年来,気管支喘息および気管支拡張症にて治療を受けている.
現病歴:1976年4月頃から臍部周辺にしくしくする自発痛が出現し,食後嘔気,嘔吐が度重なるようになり,同年5月27日当科を受診した.胃X線,内視鏡検査を施行しBorrmann1型胃癌と診断し,7月30日内科治療の目的で入院させた.
A 70 yeara-old woman with a long history of bronchial asthma visited Gunma Cancer Center Hospital on May 27, 1976, because of abdominal pain, nausea, vomiting. The first x-ray and endoscopic examination of the stomach revealed a great lobulated mass in the antrum. Multiple biopsy specimens taken from the mass were proved to be adenocarcinoma.
The patient was admitted and treated with MFC (MMC 4mg, 5 FU 500mg, CA 40mg) five times. Because the severe attacks of asthma frequently occurred, she was discharged from the hospital for climatotherapy. Subsequently, she was treated with FT 207 400 mg orally every day.
In October 1978, radiological study of the stomach disclosed no tumor shadow. At the same time, gastroscopy showed only a red spot with converging folds on the greater curvature of the antrum. In a study of biopsy specimens from the region, no cancer cells could be obtained. Total dose of FT 207 was 249.2 g until October 11, 1978.
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