Borrmann 1 Type Gastric Cancer with Remarkable Protein Loss, Report of a Case Makoto Watase 1 , Sadao Noguchi 1 , Naoki Fujimoto 1 , Masamitsu Tamai 2 1Department of Surgery, Nishinomiya Municipal Central Hospital 2Department of Clinical Pathology, Nishinomiya Municipal Central Hospital pp.1187-1192
Published Date 1989/10/25
DOI https://doi.org/10.11477/mf.1403106597
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 The case is of a 57-year-old man with marked ascites, diarrhea and edema of the extremities. Until his admission to our hospital he had been drinking heavily. Laboratory examinations on admission revealed severe hypoproteinemia (serum protein 3.7 g/dl, serum albumin 1.4 g/dl), but liver cirrhosis was denied by laboratory examinations, ultrasonic examination and computed tomography of the liver.

 X-ray and endoscopic examination of the stomach revealed large Borrmann 1 type gastric cancer, and cytological examination of ascites ruled out peritonitis carcinomatosa. In spite of total parenteral nutrition, his hypoproteinemia did not improve at all.

 Then, we came to the conclusion that the hypoproteinemia of this patient was induced by protein loss from the surface of the tumor in the stomach and we performed distal gastrectomy. After this operation, serum protein level rose up to 7.0 g/dl in a week. Specimen of the resected stomach consisted of a large cauliflower-like Borrmann 1 type cancer (14×8×4.5 cm), and histological diagnosis was that of well differentiated tubular adenocarcinoma.

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