中枢神経

Lymphomas in the central nervous system

中枢神経系には従来ないと思われていたリンパ流としてglymphatic systemが近年解明され，中枢神経系に生じるリンパ腫にもさらに関心が集まっている。中枢神経系のリンパ腫は実質内と髄膜からの発生があり，孤発あるいは多発病変として発現する。したがって，中枢神経原発かあるいは他臓器全身からの転移か，に区別する必要がある。画像診断は全身を検索することによりその役割も果たす。

In recent years, the glymphatic system has been elucidated as a lymphatic flow in the central nervous system, which was previously thought not to exist, and lymphomas occurring in the central nervous system have attracted further interest. Lymphomas in the central nervous system can arise from the parenchyma or meninges, and can appear as solitary or multiple lesions. Therefore, it is necessary to distinguish whether the tumor is primary in the central nervous system or metastasis from other organs throughout the body. Diagnostic imaging also plays a role by examining the entire body. In this article, we will explain primary diffuse large B-cell lymphoma, immunodeficiency-associated central nervous system lymphoma, and intravascular lymphoma, and also mention lymphomatoid granulomatosis.