小児慢性副鼻腔炎の細菌学的検討

Microbiological Studies of Chronic Infantile Sinusitis

I．はじめに

　慢性副鼻腔炎の成立に関しては細菌感染が一つの大きな要因であることはいうまでもなく，その観点より多数の先人の研究報告がなされてきた。その報告よりみるとサルファ剤や抗生剤の開発とともに副鼻腔炎の細菌にもかなりの変遷がうかがえる。とくに最近の抗生剤の発達やその使用量の増加は目覚しく，その動向が注目されるところである。

　今回私どもは小児の慢性副鼻腔炎患者を中心に，その上顎洞内細菌について過去の報告と私どものデータを比較し，その変遷について検討を加えたので報告する。

　Recent advance of antibiotics seem to produce a significant influence on causative microorganisms of chronic sinusitis.

　This investigation was undertaken to clarify the change in the distribution pattern of causative organisms in the maxillary sinus mainly in patients with chronic infantile sinusitis in comparison withthe previous reports.

　The materials were taken by puncture through the lateral wall of the inferior nasal meatus. The results were as follows.

　1) Gram-negative bacteria ( 71.7 %) was over-whelmingly positive ones (16.7 %) .

　2) H. Influenzae represented the greater part (51.8%) of gram-negative bacteria and P. Aeruginosa was also detected, though in a small percentage (6.7%).

　3) The detection rate of anaerobic was 8.3% for infants and 36.8% for adults.

　4) It revealed that gram-positive bacteria have been decreasing in number, while gram-negative organisms have been increasing in number.