急性化膿性中耳炎の治療成績に関する小統計

　Ⅰ．緒言

　抗生物質並びにサルフア剤の出現によつて，急性化膿性中耳炎の治療法に於いても，革命的変化がもたらされ，一つには治療日数の顕著な短縮となり，一つには乳様突起炎乃至頭蓋内合併症の激減となつて現われ，之等の事実は日常の臨床に於いて，親しく経験されるので，今更問題とするに足りない。

　然しその治療成績の向上は，化学療法以前の時代に比較して数字的には如何なる程度であろうか乳様突起炎等に就ては既に発表されたものがあるが，ペニシリンによる治療成績に関しては未だ原著となつたものが見当らない。

Fujino compares the results of treatment in acute otitis media as obtained during the days pre-antibiotics contrasted with that after the advent of antibiotics. The number of cases studied amounted to 93 that categorically belong to the former era as against 374 belonging to the latter. Listing the results in descending order from exellent, good, fair and bad, exel-lent results are obtained when penicillin dosa-ge used was adequate in amount: good with use of similar doasge of sulfa-drugs. Poor results are obtained with uses of penicillin in doses in-adequate in amount: likewise in results and do-ses with use of sulfa-drugs. The sulfa-drugs mentioned here consisted chiefly of sulfathiazol,

However, it is to be noted that, the good re-sults obtaiped during the period pre-antibiotic might be considered as equal to that regarded as poor after the advent of penicillin.

The author concludes that in face of danger with impending allergic reactions by use of pe-nicillin there is the necessity of giving a reco-nsideration to the value of sulfa-drugs, in tre-atment of acute otitis media, when the poten-cy of this agent falls only slightly below that of the penicillin.