寒冷の急性扁桃腺炎に及ぼす影響の實驗的研究

　緒言

　急性扁桃腺炎（所謂アンギーナ以下「ア」と略記）の起炎菌としては溶血性連鎖状球菌（以下溶連菌と略記）がその主役を演する事は，今日一般に認められているが，その成立機轉については，1）體外傳染説．2）自己傳染説．3）シエーネアンの淋巴管傳染説．4，フアインの「アンギノーゼ」説等幾多の假説があるが，未だ確定されていない．

　此等假説中最も信用されている體外傳染説（アシヨフ，キリアン等）の説明に必要缺くべからざる事は，溶連菌の動物の口蓋扁桃腺（以上「扁」と略記）に塗布して「ア」の發生を見る事にして，之を目的とした實驗的研究は，豊田・川名（1）戈（2）・根尾（3）・藤田（4）・Kranspe（5）・林（6）・上田（7）等多數の報告があるが，或は感染を惹起する事に成功し，或は陰性の結果に終り，諸家の所説は甲論乙駁の状態にしてその成績は一致しない．

　TOMITA AND TAKAHASHI say that no reaction whatever of inflammatory nature was evoked when the tonsils of a normal full-grown rabbit was painted witha swab of fluid medium which held in suspension aculttire of hemolytic streptococci. But tonsillitis was established when such animals were exposed to cold in a cold room where the temperature was kept constantly at 25 to 30 degrees centigrade below zero.

　The same method of innoculation was carried out then with traumatization of the tonsils. The degree of infection was now greatest in those animals which were previouly exposed to cord anteceding the innoculation:those whic. hwere exposed during traumatizing procedure followed next in order:while, those which were exposed after the procedure were the slightest affected. In view of these facts, the authors maintain that, cold is cledrly and strongly a contributory factor in the onset of tonsillitis and serve as well a medium by which to aggravate the general situation.