長崎大学最近10年間の網膜色素変性症患者について

Retinitis pigmentosa. A 10-year review of patients treated at Nagasaki University Hospital

　最近10年間に長崎大学附属病院眼科を受診した網膜色素変性症患者について統計的考察を行った。対象は男性97人，女性83人の合計180人，353眼で，外来新患患者の0.7％であった。定型例が332眼94.5％，非定型例が21眼5.9％で，初診時の平均年齢は47.5歳であった。この10年間で患者数の著明な増減はなかった。定型例の視力と視野は，年齢の上昇にともない悪化例の割合が高くなった。合併症は白内障が169眼と最も多く，緑内障16眼，角膜混濁10眼を認め，屈折異常は近視が多かった。眼底所見を，網膜混濁，色素沈着，血管狭細，視神経萎縮に分類したが，前二者は年齢と共に悪化例の割合が高くなった。後二者は年齢とは無関係であった。本院における本疾患の特徴として，高齢者でも視力が良好であり男女差が小さかった。

A statistical study was made of retinitis pig-mentosa (RP) at the Nagasaki University Hospital in the last 10 years. The number of patients with a diagnosis of RP was 180 (97 males and 83 females), 353 eyes. The incidence was 0.7% among out-patients. The typical classical form of RP was found in 332 eyes (94.1%), and the atypical form in 21 eyes (5.9%). The average age of RP patients was 47.5 years at the initial visit to this hospital. There was no increase of RP patients in the past 10 years. In patients with the typical form of RP, visual acuity and visual fields became worse as they grew older. Myopia was a common refractive error. Ocular complications included cataract in 159 eyes, glaucoma in 16 eyes and corneal opacities in 10 eyes. RP patients were classified by ocular fundus findings (retinal opacity, retinal pigmentation, nar-rowing of vessels and optic nerve atrophy). Retinal opacity and retinal pigmentation became worse with age, but age was not related to narrowing of vessels or optic nerve atrophy.