シリコーンオイル注入併用硝子体手術例における術後増殖膜発症要因

Factors for epiretinal membrane formation after silicone oil tamponade

　シリコーンオイル注入を併用した硝子体手術後に発症する増殖性硝子体網膜症（PVR）の全身的，局所的要因を検討した。症例は，過去18か月間に手術を行った57眼，男性32例34眼，女性22例23眼で，平均年齢は60歳である。原疾患は，裂孔原性網膜剥離20眼，糖尿病網膜症15眼，加齢黄斑変性15眼，脈絡膜新生血管6眼，眼内炎1眼であった。PVRは17眼（30％）に生じ，他の40眼には生じなかった。PVR発症は，基礎疾患，年齢，性別など全身的要因のいずれとも相関せず，手術回数とシリコーンオイル貯留期問とも相関しなかったが，網膜冷凍凝固術の併用時には有意に多く，網膜剥離の範囲が1象限未満のときに有意に少なかった。PVRの発症が網膜冷凍凝固術と網膜剥離の範囲に関係するという以上の結果は，従来の報告と一致する。

We reviewed 57 eyes treated by vitreous surgery with adjunctive silicone oil tamponade during the past 18 months. We evaluated the systemic and local factors that are involved in proliferative vitreoretinopathy (PVR) after surgery. The series comprised 34 eyes of 32 males and 23 eyes of 22 females. Their ages averaged 60 years. Surgery was performed for rhegmatogenous retinal detachment 20 eyes, diabetic retinopathy 15 eyes, age-related macular de-generation 15 eyes, choroidal neovascularization 6 eyes, and endophthalmitis 1 eye. PVR developed postoperatively in 17 eyes (30%). There was no significant correlation between PVR and systemic factors including underlying disease, age or gender of patients. PVR was correlated neither with the number of surgeries nor with the duration of intraocu-lar silicone oil. PVR was significantly more frequent in eyes receiving cryocoagulation and less in eyes with retinal de-tachment involving one quadrant or less. These last findings are in accord with the past reports.