中心性漿液性脈絡網膜症の蛍光漏出部の眼底自発蛍光

Fundus autofluorescence of sites with dye leakage in central serous chorioretinopathy

要約　目的：中心性漿液性脈絡網膜症のフルオレセイン漏出部の眼底自発蛍光の報告。対象と方法：初回発症の12例12眼を対象とした。男性9名，女性3名，年齢は33～67歳，平均51歳であった。CX-1^TM（キヤノン社製）で眼底自発蛍光を記録した。結果：全例で色素漏出部は低蛍光を呈した。その近傍に9眼で過蛍光があった。色素漏出が1個の7眼では，低自発蛍光部が4眼で1個，3眼で複数個あった。色素漏出が2個の2眼では複数個の低蛍光，3個以上の3眼ではそれ以上の数の低蛍光があった。再発した2眼では，初発時に光凝固をしなかった低蛍光部から色素漏出があった。結論：中心性漿液性脈絡網膜症での眼底自発蛍光は，色素漏出部が低蛍光を呈し，その近傍に過蛍光のあることが多い。低蛍光部の数は色素漏出部と同数またはそれ以上である。再発時の色素漏出は，初回発症時の低蛍光部に生じる傾向がある。

Abstract.　Purpose：To report fundus autofluorescence in eyes with central serous chorioretinopathy. Cases and Method：This retrospective study was made on 12 eyes of 12 cases during the initial episode of the disease. The series comprised 9 males and 3 females. The age ranged from 33 to 67 years, average 51 years. Fundus autofluorescence was recorded with a fundus camera（CX-1^TM, Canon）. Findings：All the eyes showed hypofluorescence in the site of fluorescein dye leakage. Nine eyes showed hyperfluorescence adjunct to the site. In 7 eyes with single site of dye leakage, area of hypoautofluorescence numbered one in 4 eyes and multiple in 3. Multiple areas of hypofluorescence were present in 2 eyes with 2 sites of dye leakage. Those of hypofluorescence numbered 3 or more in 3 eyes with more than 3 sites of dye leakage. In 2 eyes during recurrence of the disease, dye leakage was located at the previous area of hypofluorescnce not treated by photocoagulation. Conclusion：In central serous chorioretinopathy, sites of dye leakage may show hypoautofluorescence with hyperautofluorescence in the neighboring area. Number of hypoautofluorescence may be equal to or more to that of dye leakage. During recurrence of the disease, dye leakage may develop at the site of hypoautofluorescence during the previous attack.