漿液性網膜剝離型加齢黄斑変性と中心性漿液性脈絡網膜症の眼底自発蛍光の比較

Findings by fundus autofluorescence in central serous retinopathy and age-related macular degeneration with serous retinal detachment

要約　目的：漿液性網膜剝離を伴う加齢黄斑変性（SRD-AMD）と中心性漿液性脈絡網膜症（CSC）の眼底自発蛍光の報告。

対象と方法：SRD-AMDは14眼で，59〜76歳（平均67歳），CSCは24眼で，33〜68歳（平均48歳）である。眼底自発蛍光にはキヤノン社製CX-1を用いた。

結果：SRD-AMDの蛍光造影は，全例occult CNV型の過蛍光で，CSCは円形漏出19眼，吹き上げ型5眼であった。SRD-AMDの眼底自発蛍光では，全例でoccult CNV部の低蛍光があり，12眼で枝状，1眼で地図状，1眼で点状であった。CSCの眼底自発蛍光では，23眼で蛍光漏出部の低蛍光があり，16眼で点状，5眼で点の集合，2眼で枝状であった。

結論：SRD-AMDの眼底自発蛍光は，枝状の低蛍光を示すことが多く，CSCでは，点および点の集合の低蛍光を示すことが多い。

Abstract　Purpose: To report and compare findings by fundus autofluorescence in central serous retinopathy（CSC）and age-related macular degeneration（AMD）with serous retinal detachment.

Cases and Method: This retrospective study was made on 24 eyes with CSC and 14 eyes with AMD and serous retinal detachment. The age of patients with CSC ranged from 33 to 68 years, average 48 years. The age of patients with AMD and serous retinal detachment ranged from 59 to 76 years, average 67 years. All the eyes were evaluated for autofluorescence by Canon CX-1 fundus camera.

Findings: Fluorescein angiography in eyes with CSC showed inkblot leakage in 19 eyes, and upward leakage in 5 eyes. All the eyes with AMD showed occult choroidal neovascularization（CNV）. Fundus autofluorescence showed hypofluorescence at the site of dye leakage in 23 out of 24 eyes with CSC. Autofluorescence showed dot-like pattern in 16 eyes, fused dot-like pattern in 5 eyes, and branched pattern in 2 eyes. All the eyes with AMD showed hypoautofluorescence at the sites of occult CNV seen by fluorescein angiography. The hypoautofluorescence showed branched pattern in 12 eyes, geographic pattern in 1 eye, and dot-like pattern in 1 eye.

Conclusion: Eyes with CSC showed, predominantly, dot-like or fused dot-like hypoautofluorescence. Eyes with AMD often showed branched pattern of hypoautofluorescence.