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Quantitative Anylysis of Cerebrospinal Fluid Dynamics in Syringomyelia Using cine MRI with Pre-Saturation Hitoshi Matsuzawa 1 , Kazutoshi Hida 1 , Kiyohiro Houkin 1 , Iwasaki Yoshinobu 1 , Hiroshi Abe 1 , Minoru Akino 2 , Hisatoshi Saito 2 1Department of Neurosurgery, Hokkaido University School of Medicine 2Sapporo Azabu Neurosurgical Hospital Keyword: magnetic resonance imaging(MRI) , cerebro spinal fluid , intra cranial pressure , Chiari malformation , syringomyelia pp.24-29
Published Date 1992/1/1
DOI https://doi.org/10.11477/mf.1406902052

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  • Abstract
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Some reports show the qualitative analysis of cerebrospinal fluid (CSF) pulsation in the subarach-noid space and the syrinx using cine magnetic reso-nance imaging (MRI) . However, few reports stud-ied the quantitative analysis of CSF pulsation. We report here the results of quantitative analysis of CSF pulsation using the cine MRI with pre-satura-tion pulse. Using flow phantom, we calibrated the correlation between the true velocity and calculated velocity acquired from the movement of pre-satur-ated low signal. Three cases of syringomyelia with Chiari malformation, two cases of traumatic syrin-gomyelia, and three normal volunteers were examined using this technique, and we could obtain time-velocity curves of CSF in both subarachnoid spaces and syrinx.

Although obvious pulsation of CSF was observed in the syrinx of all Chiari malformations, no pulsa-tion of CSF was observed in the syrinx of traumatic syringomyelia. CSF in the syrinx moves upward in the early systolic cardiac cycle, dOwnward in the systolic cycle, and upward again in the diastolic cycle. Patterns of CSF pulsation in syrinx were similar to those in the subarachnoid space, but "phase" of these pulsations differed from case to case.

These results suggest the close relationship between CSF pulsation in the syrinx and CSF obstruction at the cranio-vertebral junction. Disso-ciation of the "phase" of CSF pulsation in the syrinx and subarachnoid space may be significant in the analysis of the pathogenesis of syringomyelia.


Copyright © 1992, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

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