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Japanese

Longitudinal Change of H-1 Spectroscopy in Cerebral Infarction Kiyohiro Houkin 1 , Hitoshi Matsuzawa 1 , Kazuo Miyasaka 1 , Hiroyasu Kamiyama 2 , Yoshinobu Iwasaki 2 , Hiroshi Abe 2 , Kazutoshi Hida 3 , Mitsuyuki Koiwa 3 , Takeshi Kashiwaba 3 1Department of Radiology, Hokkaido University 2Neurosurgery, Hokkaido University 3Kashiwaba Neurosurgical Hospital Keyword: proton nuclear magnetic resonance spectroscopy , magnetic resonacec spectroscopy(MRS) , cerebral infarction , lactic acid , N-acetyl-aspartate pp.583-587
Published Date 1991/6/1
DOI https://doi.org/10.11477/mf.1406900212
  • Abstract
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Longitudinal change of the proton spectroscopy was observed in 2 cases of cerebral infarction. Proton spectra was acquired utilizing stimulated echo acquisition mode (STEAM) . In acute stage, the increase of lactic acid and decrease of N-acetyl-aspartic acid (NAA) was observed prior to the appearance of abnormality in imagings such as magnetic resonance imaging and computer tomo-graphy. The increase of lactic acid was observed in subacute stage and chronic stage (in severe case). The decrease of NAA persisted in chronic stage.

The increase of lactic acid and decrease of NAA indicate a damage of the ischemic tissue. The degree of the decrease of the NAA seems to be a reasonable indicator of the viability of the damaged tissue. The proton spectroscopy is a powerful modality for the evaluation of the extent of tissue damage caused by the ischemic insult.


Copyright © 1991, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

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