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Body surface distribution of QTc interval in patients with hypertrophic cardiomyopathy Yoshiji Yamada 1 , Hiroshi Hayashi 1 , Shinji Watabe 1 , Tomihisa Ishikawa 1 1First Department of Internal Medicine, Nagoya University School of Medicine pp.1211-1215
Published Date 1988/11/15
DOI https://doi.org/10.11477/mf.1404205361

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  • Abstract
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The purpose of the study was to examine body surface distribution of QTc interval in normal sub-jects and patients with hypertrophic cardiomyopathy and to study the effect of regional ventricular hyper-trophy on spatial distribution of QTc interval.

Eighty-seven-lead unipolar electrocardiograms were recorded simultaneously from 50 normal sub-jects (group N), 21 patients with septal hypertrophy (group SH) and 10 patients with apical hypertrophy (group AH). QT interval was measured in each lead and QTc isointerval map was constructed.

Mean of all QTc values of groups SH and AH (398±9 and 402±12 msec, respectively) were signifi-cantly longer (p<0.005) than that of group N (364 ±10 msec). In group N, the relatively longer QTc intervals were observed in the left precordium to left lower back and in the right shoulder. In groups SH and AH, the relatively longer QTc intervals were observed in the left precordium to left lateral chest and in the right upper chest to right shoulder. The difference between these two groups was that two areas with relatively longer QTc interval in group SH merged at the midsternal portion. These results may suggest that body surface distribution of QTc interval is influenced by regional ventricular hypertrophy, that is, abnormal ventricular excitation sequences due to hypertrophy of myocardium are reflected as the prolongation of QTc interval at the body surface.


Copyright © 1988, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1200 印刷版ISSN 0452-3458 医学書院

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