薬剤性急性食道潰瘍の1例

Esophageal Ulceration Associated with Voltaren Therapy, Report of a Case

　治療の目的で用いられた薬剤による急性食道潰瘍の報告はまれであるが，近年，診断学の進歩により報告数も増加している．われわれは，消炎鎮痛剤sodiu m2-phenylacetate（ボルタレン）に起因すると考えられる急性食道潰瘍の1例を経験したので報告する．

　Esophageal ulceration secondary to medicinal agents has rarely been reported. We have treated a patient with esophageal ulceration associated with the ingestion of sodium 2-phenylacetate (a volteren tablet).

　A 23-year-old woman came to us because of the onset of severe, retrosternal burning pain that awakened her from sleep. She has taken a voltaren tablet without water and promptly gone to sleep, as self-treatment of a “common cold”.

　Esophageal roentgenogram and esophagoscopy revealed five large, discrete ulcers located 26 cm from incisors.

　She was treated with antacids and a bland diet and improved rapidly. Esophageal roentgenogram one month later showed no vestige of ulcers.